Isaac and Catherine were first cousins.
Frederick Co VA. On 3 Apr 1797, Benjamin & Catherine Fry sold to Isaac Frye three tracts totalling 233 acres for 300#'s. The first tract, 56 acres was part of 300 acres conveyed by John Branson to Paul Froman and by him to Abraham Ferree and by Ferree to the said Benjamin Frye. The second tract was 159 acres, part of 353 acres granted to Paul Froman, sold to Abraham Ferree and then to Benjamin Frye. The third tract was 18 acres adjoining the others, part of 444 acres granted 3 Jan 1775 to Benjamin Frye. All parties were of Frederick Co. Benjamin signed with his mark; Catherine apparently signed her own name. Wit: Joseph Longacre, Nathaniel Cartmell, and Joseph Fawcett. Frederick Co DB 25, p.59-61.
Isaac was in Clay Co MO by 1822, when he was noted as being a jury foreman.
Isaac and Catherine are buried in the Fry Cemetery on the McCulloch farm, Hardin Twp, Clinton Co, MO.
Isaac FRY and Catherine FRYE were married on 19 April 1791 in Frederick County, Virginia.11,42 Catherine FRYE, daughter of Jacob FRYE and Mary [FRYE], was born on 5 August 1773.38 She died on 14 March 1857 at the age of 83 in Clinton County, Missouri.38
Catherine died aged 83 years, 7 months, 9 days, which calculates to 4 Aug 1773.
Isaac FRY and Catherine FRYE had the following children: