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Haplogroup R1b (DYS393=14)

While most R1b signatures in Western Europe exhibit a DYS393 marker value of 13, a few

of the "Border Reiver" descendants have a value of 14. This may or may not be significant.

Studies conducted on the frequency of mutation events among

Y chromosome DNA markers indicate that DYS393 has the lowest mutation rate of the 12

main markers used to identify a haplotype. The Kayser study of 2000 demonstrated a

mutation rate of zero for DYS392 and DYS393, while the Heyer study of 1997 recorded

a mutation of zero for DYS390 and DYS393.  Only DYS393 had a mutation rate of zero

in both studies. That does not mean that DYS393 never mutates, but it does suggest that

it mutates very rarely.

Therefore, a DYS393 marker value of 14 may signify an as yet unidentified subclade of R1b,

or may simply be the result of a random mutation. We have obtained match patterns for the

haplotypes in our sample that exhibit this value, and will discuss them below.

Haplotypes with a DYS393 marker value of 14 appear to be divided into two moieties,

one with a western orientation as exemplified by the Basques, and another with an eastern

orientation like that of the Hazara in Pakistan.

However, since all of the matches here were derived from YHRD, which does

not provide the SNP-tested haplogroups of its entries, it is likely that the matches

among the Hazara do not belong to R1b at all, but to haplogroup "R".

If the Hazara matches are R1b, it is possible that the DYS393 marker value of 14 represents

a Paleolithic variant of R1b that was preserved separately in both the Pyrenees and Central Asia

during the Ice Age. Afterwards, the surviving carriers of this variant would have radiated

outward both east and west. This would account for the occurrence of haplotypes

with this DYS393 marker value over a wide range of territory.

An alternative explanation for the wide geographical range of DYS393=14 R1b

haplotypes would be, of course, that they result mostly from local mutations, and are

therefore alike in "state" but not in "descent".

R1b DYS393=14 Haplotype #1

The matches in New Guinea, and with the Chinese in the UK, may be either European in origin - or, possibly, the results of

convergence with one or more Asiatic haplogroups.

The European matches all appear in areas where there has been a Germanic influence. Wroclaw is a traditionally German area

of Poland, Mecklenberg is on the Baltic Coast, Strasbourg was settled by Swabians and Burgundians - also both supposedly

from the Baltic - and Emilia Romagna was colonized by Lombards and Ostrogoths.

The one Hispanic match notwithstanding, this haplotype does not exhibit an especially Celtic or Iberian match pattern. It may

be associated with the Eastern Germanic tribes, and might have come to Britain with Roman troops of Germanic descent -

or with the Anglo-Saxon invasion.

19 389i 389ii 390 391 392 393 385a 385b
14 13 29 25 11 13 14 - -

Geographical Locale

%
Highland Papua New Guinea 3.45
Uppsala, Sweden 1.75
Connecticut [Hispanic-American] 1.52
Emilia Romagna, Central Italy 1.12
Strasbourg, Alsace 1.01
England-Wales [Chinese] .93
Wroclaw, Western Poland .83
London, England .70
Rostock, Mecklenburg .49

R1b DYS393=14 Haplotype #2

Five of the top ten frequencies for the haplotype below fall in Brazil, Asturias in Northern Spain, and among three sets of

American Hispanics. The other five include New Guinea (most likely of European origin), Central Greece (based on

one hit in a tiny sample of 14), a Celtic part of Austria called Graz, Friesland and among European-Americans in Louisiana.

No truly coherent trends can be inferred from such a mixed bag.

Of the next ten frequencies, four fall in Iberia or Latin America, and five fall in European areas with a strong Celtic past such

as Austria, Northern Italy, The Rhineland and England. As always with R1b haplotypes, interpretation is difficult. The bias

towards Iberia over Germanic areas, as well as the inclusion of known European Celtic areas, suggest that the haplotype most

likely came to Britain with the Iberians or the Celts in pre-Roman times.

19 389i 389ii 390 391 392 393 385a 385b
14 13 29 24 11 13 14 - -

Geographical Locale

%
Maryland [Hispanic-American] 7.69
Central Greece 7.14
Highland Papua New Guinea 3.45
Louisiana [European-American] 3.23
Pennsylvania [Hispanic-American] 3.13
Graz, Styria 3.08
Rio de Janeiro, Brazil [European] 2.38
Friesland, Northern Netherlands 2.27
Asturias, Northern Spain 2.22
Virginia [Hispanic-American] 2.17
Birmingham, England 2.06
Madeira, Portugal 2.04
Strasbourg, Alsace 2.02
Cordoba, Argentina 2.00
Marche, Eastern Italy 1.85
Northern Spain [Basque] 1.79
Missouri [European-American] 1.69
Pyrenees, Spain 1.52
Vienna, Austria 1.52
Cologne, Westphalia 1.48
Netherlands 1.14
Sao Paulo, Brazil [European] 1.12
London, England 1.05
Cantabria, Northern Spain .99
Mainz, Rhineland-Palatinate .96
Krakow, Poland .93
Paris, France .92
Ljubljana, Slovenia .83
Bulgaria .82
Choco, Colombia [African] .75
Magdeburg, Saxony-Anhalt .71
Riga, Latvia .69
Argentina [European] .66
Ireland .66
Lombardy, Northern Italy .55
Northern Portugal .55
Central Portugal .54
Rostock, Mecklenberg .49
Freiburg, Baden-Wurttemburg .46
Tuscany, Central Italy .46
Barcelona, Catalonia .45
Tyrol, Austria .43
Warsaw, Poland .42
Munich, Bavaria .39
Chemnitz, Saxony .37
Sweden .25
Berlin, Brandenburg .18
Gdansk, Northern Poland .18
Leipzig, Saxony .15

R1b DYS393=14 Haplotype #3

This haplotype has a very unusual match pattern. The Hazara of Pakistan are an Indo-Iranian speaking minority of mixed

Mongol and Indo-Iranian ancestry. If the high frequency of matches with this group are not the result of convergence

with an "R" haplotype, it could suggest an origin among the Indo-Iranian nomads of Central Asia. This haplotype, in that

case, could have come to Britain with Roman troops, or with the descendants of Huns.

19 389i 389ii 390 391 392 393 385a 385b
14 - - 22 11 13 14 - -

Geographical Locale

%
Pakistan [Hazara] 8.70
Lublin, Eastern Poland .75
Argentina [Europeans] .33

R1b DYS393=14 Haplotype #4

This partial haplotype suggests an Celtiberian origin, with its highest frequencies among Basques and in a Celtic region

of Northern Spain.

19 389i 389ii 390 391 392 393 385a 385b
14 12 - 23 11 13 14 - -

Geographical Locale

%
Northern Spain [Basque] 1.19
Asturias, Northern Spain 1.11
Warsaw, Central Poland .42
Berlin, Brandenburg .18

R1b DYS393=14 Haplotype #5

By far, the highest frequency for this haplotype falls among the Hazara, a minority in Pakistan of mixed Mongol and

Indo-Iranian origin. The third highest freqnency falls among the Basques. A genetic (as well as a linguistic) similarity

has been reported between the Basques and certain people of the Caucasus, and this haplotype may be a manifestation

of that similarity.

This haplotype might have either a western or an eastern origin in anyone who carries it - but these groups are not necessarily

related. The greatest likelihood is that the matches among the Hazara are the result of convergence with a Central Asiatic

haplotype belonging to haplogroup "R".

Since the most of the other high frequencies here fall in such places as Northern Spain, Ireland, England, Austria, the Rhineland

and The Netherlands, this haplotype may well have come to Britain with prehistoric Iberian migrants or with a later wave of Celtic

settlement from Central Europe.

The Dutch and Germanic elements in the match pattern - plus the Teutonic DYS390 value

of 23 - suggest that an origin among the Anglo-Saxons or the Flemish allies of the Normans

are also strong possibilities.

19 389i 389ii 390 391 392 393 385a 385b
14 - - 23 11 13 14 - -

Geographical Locale

%
Pakistan [Hazara] 39.13
Liguria, Western Italy 2.47
Northern Spain [Basque] 2.38
Friesland, Northern Netherlands 2.27
Birmingham, England 2.06
Limburg, Southern Netherlands 2.00
Cantabria, Northern Spain 1.98
Vienna, Austria 1.52
Dresden, Saxony 1.47
Ireland 1.32
Texas [European-American] 1.28
Asturias, Spain 1.09
Leiden, Netherlands 1.04
Strasbourg, Alsace 1.01
Cape Town, South Africa [European] 1.00
Freiburg, Baden-Wurttemburg .92
Southern Portugal .89
Hamburg, Northern Germany .88
Rio de Janeiro, Brazil [European] .79
Tartu, Estonia .75
Dusseldorf, Westphalia .67
Sao Paulo, Brazil [European] .67
Bialystok, Poland .55
Lombardy, Northern Italy .55
Antioquia, Colombia [European] .49
Rostock, Mecklenburg .49
Leipzig, Saxony .45
Warsaw, Central Poland .42
Berlin, Brandenburg .36
London, England .35
London, England [Afro-Caribbean] .34
Argentina [European] .33
Northern Portugal .32
Finland .25
Sweden .25
Gdansk, Poland .18
Chemnitz, Saxony .12

R1b DYS393=14 Haplotype #6

Most of the hits for this partial haplotype fall in Italy, Spain and among Latin Americans. The orientation seems to be Iberian

and Mediterranean. Such a haplotype may have entered Britain with prehistoric Iberian migrants, or with Roman colonization

two thousand years ago. It is most likely not Germanic.

19 389i 389ii 390 391 392 393 385a 385b
14 14 - 24 11 13 14 - -

Geographical Locale

%
Florida [Hispanic-American] 4.35
Umbria, Central Italy 3.92
Caceres, Central-West Spain 2.19
Oregon [African-American] 2.13
Virginia [European-American] 1.64
Cordoba, Argentina 1.00
Marche, Eastern Italy .93
Zaragoza, Spain .83
Rio de Janeiro, Brazil [European] .79
Pyrenees, Spain .75
Cologne, Westphalia .74
Valencia, Eastern Spain .71
London, England .70
Bialystok, Poland [Byelorussians] .64
Freiburg, Baden-Wurttemburg .46
Latium, Central Italy .45
Northern Portugal .32
Sao Paulo, Brazil [European] .22
Berlin, Brandenburg .18
Leipzig, Saxony .15

R1b DYS393=14 Haplotype #7

The haplotype below is also definitely not Germanic. It could be Iberian or Central European Celtic, and as such may have

entered Britain with the prehistoric Iberians or the Celts who brought their language circa or 500 B.C.E. There is a strong bias

towards Southern Europe, including Italy. This suggests the additional possibility that this haplotype might have come

to Britain with Roman settlers, or others of Southern European origin.

19 389i 389ii 390 391 392 393 385a 385b
14 13 30 24 10 13 14 - -

Geographical Locale

%
Limburg, Netherlands 2.00
Liguria, Western Italy 1.23
Lombardy, Northern Italy .55

R1b DYS393=14 Haplotype #8

The haplotype below is very uncommon, but the few matches occur in Hispanic samples.

It may have come to Britain with the prehistoric Iberians who became the Picts.

19 389i 389ii 390 391 392 393 385a 385b
14 12 28 24 10 13 14 - -

Geographical Locale

%
Texas [Hispanic-American] 1.35
Andulacia, Southern Spain .61

R1b DYS393=14 Haplotype #9

The haplotype below exhibits its highest frequencies in Iberia, and in areas with a strong Celtic past - e.g., Ireland, Belgium

and Switzerland. This haplotype most likely came to Britain with prehistoric Iberians, or during a later Celtic migration from

continental Europe.

19 389i 389ii 390 391 392 393 385a 385b
14 13 29 24 10 13 14 11 14

Geographical Locale

%
Asturias, Northern Spain 2.22
Bolivia [Amerindian] 1.64
Madrid, Spain 1.35
Texas [European-American] 1.28
Brussels, Belgium .80
Switzerland .67
Ireland .66
Andulacia, Southern Spain .61
Greifswald, Pomerania .48
Barcelona, Catalonia .45
Central Portugal .43
Northern Portugal .32
Sweden .25
Chemnitz, Saxony .24
Freiburg, Baden-Wurttemburg .23
Stuttgart, Baden-Wurttemburg .22

R1b DYS393=14 Haplotype #10

A match in Norway is more typical of haplotypes with a DYS390 marker value of 23 and a DYS393 marker value of 12.

There is, however, some question as to whether this YHRD match is even R1b. The DYS385a,b marker values were 14,17

- more typical of haplogroup Q than R1b.

One is tempted to say that the "Border Reiver" profile that matches this single YHRD entry is of Viking origin, but one

match is scanty evidence of anything - even if this is a legitimate R1b.

19 389i 389ii 390 391 392 393 385a 385b
14 12 29 23 10 13 14 - -

Geographical Locale

%
Western Norway 1.56

R1b DYS393=14 Haplotype #11

The haplotype below has no matches in Iberia. The few European matches all fall in Germanic-language speaking nations.

The origin of the Brazilian match is indeterminate, while the match in Mongolia is probably the result of convergence with an

"R" haplotype. This haplotype may have originated with the Danes or the Anglo-Saxons. The European-American hits

in two relatively southerly areas of the United States could support an Anglo-Saxon or Germanic origin.

19 389i 389ii 390 391 392 393 385a 385b
14 14 30 24 10 13 14 - -

Geographical Locale

%
Mongolia [Khalkh] 2.56
Maryland [European-American] 1.56
Texas [European-American] 1.28
Birmingham, England 1.03
Sweden .25
Sao Paulo, Brazil [European] .22
Leipzig, Saxony .15

R1b DYS393=14 Haplotype #12

The haplotype match table below was prepared for a "Border Reiver" participant who has been SNP-tested as R1b, but

whose DNA profile closely resembles an "N" haplotype and has YHRD matches largely in Fenno-Scandinavia and Northern

Asia. This haplotype is slightly different, but is more appropriate. It is the closest equivalent in YHRD among haplotypes that

appear to be R1b. The highest European frequencies fall in The Netherlands and Saxony, followed by matches that fall

predominantly in German-speaking areas (Wroclaw, for instance, was settled by Germans). This haplotype, like several

other DYS393=14 haplotypes, could easily have come to Britain with the Anglo-Saxons or the Flemish.

19 389i 389ii 390 391 392 393 385a 385b
14 13 29 23 10 13 14 - -

Geographical Locale

%
Oregon [European-American] 2.86
Indiana [African-American] 2.70
Zeeland, Netherlands 2.17
Dresden, Saxony 1.16
Bern, Switzerland 1.10
Wroclaw, Poland .83
New York City [European-American] .65
Tuscany, Italy .46
Latium, Italy .45
Warsaw, Poland .42
Munich, Bavaria .40
Berlin, Brandenburg .18
Chemitz, Saxony .12

R1b DYS393=14 Haplotype #13

Of the ten top match frequencies in the Old World, five fall in Iberia, and one each falls in Italy, Denmark, Belgium,

Switzerland and Ireland. This is a fairly typical match pattern for modal R1b haplotype, although this one is

biased towards Iberia a little more than most.

The highest New World frequencies fall in Bolivia and among "European Americans" in the southern part of the U.S.

The Bolivian hit is most likely Iberian in origin, while those in the U.S. are very possibly of Anglo-Celtic origin.

Like many R1b haplotypes, this may have come to Britain from a variety of sources - but the most likely appear to be

prehistoric Iberians or later arrivals from the Celtic areas of Europe.

19 389i 389ii 390 391 392 393 385a 385b
14 13 29 24 10 13 14 - -

Geographical Locale

%
Texas [European-American] 2.56
Asturias, Spain 2.22
Umbria, Italy 1.96
Southern Portugal 1.79
Missouri [European-American] 1.69
Bolivia [Amerindian] 1.64
Virginia [European-American] 1.64
Denmark 1.59
Madrid, Spain 1.32
Caceres, Spain 1.10
Madeira, Portugal 1.02
Brussels, Belgium .80
Switzerland .67
Ireland .66
Stuttgart, Baden-Wurttemburg .66
Andulacia, Spain .61
Lombardy, Italy .55
Rostock, Mecklenburg .49
Greifswald, Pomerania .48
Freiburg, Baden-Wurttemburg .46
Barcelona, Catalonia .45
Central Portugal .43
Berlin, Brandenburg .36
Northern Portugal .32
Sweden .25
Chemnitz, Saxony .24
Gdansk, Poland .18

R1b DYS393=14 Haplotype #14

The match pattern below was prepared for a "Border Reiver" haplotype that was apparently SNP-tested as R1b.

This haplotype, however, looks like it should belong to haplogroup N, and the matches in Russia, Sweden and

Finland are most likely the result of convergence with N haplotypes.

The other matches, in Saxony, Switzerland and Cape Town - if they are indeed R1b - suggest an origin among

the Anglo-Saxons or the Celts.

19 389i 389ii 390 391 392 393 385a 385b
14 14 31 23 11 14 14 - -

Geographical Locale

%
Novgorod, Russia 2.00
Uppsala, Sweden 1.75
Bern, Switzerland 1.10
Cape Town, South Africa [European] 1.00
Finland .25
Leipzig, Saxony .15

R1b DYS393=14 Haplotype #15

The matches for the haplotype below were filtered by DYS438 and DYS439 values of 12, in order to restrict the

results to likely R1b haplotypes, and to screen out convergent haplotypes belonging to haplogroup N.

There was only one resulting match. This fell in Northern Italy, and really provides way too little information

to speculate on the origin of this haplotype.

A value of 14 for both DYS392 and DYS393 does not appear typical of any R1b sub-variant, and may be interpreted

as a local or a personal mutation.

19 389i 389ii 390 391 392 393 438 439
14 13 - 24 11 14 14 12 12

Geographical Locale

%
Brescia, Italy .94

R1b DYS393=14 Haplotype #16

The matches for the haplotype below were also filtered by DYS438 and DYS439 values of 12, and the results are

similarly too sparse to facilitate interpretation. Taken together, however, the results for both haplotypes vaguely suggest an

origin in Central Europe, perhaps among Celtic or Germanic populations.

19 389i 389ii 390 391 392 393 438 439
14 13 - 24 10 14 14 12 12

Geographical Locale

%
Stuttgart, Germany .44

R1b DYS393=14 Haplotype #17

The match pattern for the haplotype below so closely resembles what you would expect for an N haplotype that it

is impossible to discount convergence. The matches in Estonia, Poland, Finland, Norway and Sweden are all suspect.

The remaining European matches fall in Germany, and may or may not be N haplotypes as well. If not, this would suggest

a Germanic origin for this R1b haplotype, which is typical of R1b haplotypes with a DYS390 value of 23.

19 389i 389ii 390 391 392 393 385a 385b
14 13 - 23 11 14 14 11 14

Geographical Locale

%
Florida, USA [European] 4.55
Bialystok, Poland [Old Believers] 1.55
Tartu, Estonia .75
Muenster, Germany .51
Northern Norway .27
Finland .25
Sweden .25
Stuttgart, Germany .22
Berlin, Germany .18
Antioquia, Colombia [European] .08

R1b DYS393=14 Haplotype #18

The match for the haplotype below were filtered by a DYS438 value of 12, and the results are too sparse

to facilitate interpretation. However, the results vaguely suggest an Germanic origin.

19 389i 389ii 390 391 392 393 438
14 14 30 23 11 14 14 12

Geographical Locale

%
Bonn, Germany 1.11

R1b DYS393=14 Haplotype #19

Considering that R1b haplotypes with DYS393 values of 14 run the risk of convergence with haplotypes from

different haplogroups found in Asia, the most relevant matches for the one below are those occurring in Western Europe.

There are three such matches in Germany, and one in Belgium, suggesting an Anglo-Saxon, Flemish or some other

Germanic origin.

19 389i 389ii 390 391 392 393 385a 385b
14 13 30 24 11 13 14 11 14

Geographical Locale

%
Boyaca, Colombia [Mestizo] 2.63
Pennsylvania, USA [European] 1.49
Mainz, Germany .96
Brussels, Belgium .80
Taraz, Kazakhstan .57
Rostock, Germany .41
Buenos Aires, Argentina [European] .31
USA [African American] .28
Sao Paulo, Brazil [European] .22
Stuttgart, Germany .16
Antioquia, Colombia [Mestizo] .08

R1b DYS393=14 Haplotype #20

The haplotype below is found only in one small Scandinavian sample in YHRD, so there is no reason why

it may not have come to Britain with the Vikings.

19 389i 389ii 390 391 392 393 385a 385b
14 13 - 25 11 13 14 11 13

Geographical Locale

%
Varmland, Sweden 2.38

R1b DYS393=14 Haplotype #21

The haplotype below exhibits its highest frequencies in Spain and Italy. This suggests a possible Mediterranean origin,

but this haplotype most likely came to Britain with the prehistoric Iberians. It is also widespread at low levels among

Germanic locales, and therefore could also be of Anglo-Saxon or Viking origin.

19 389i 389ii 390 391 392 393 385a 385b
14 14 30 24 11 13 14 11 14

Geographical Locale

%
Umbria, Italy [Italian] 1.96
Caceres, Spain [Spanish] 1.09
Pyrenees, Spain [Spanish] .75
Northern Portugal [Portuguese] .70
Northern Sardinia, Italy [Italian] .50
Latium, Italy [Italian] .45
London, United Kingdom [English] .35
Central Norway [Norwegian] .32
Freiburg, Germany [German] .23
Berlin, Germany [German] .15
Cologne, Germany [German] .14
Finland [Finnish] .11
Stuttgart, Germany [German] .09

R1b DYS393=15 Haplotype #1

The top match frequency for this very rare haplotype falls among the Basques, and two of the other three fall in

Northern Italy and the Rhineland, both parts of that Central European region considered to be the home of the

Celts. This haplotype most likely came to Britain with the prehistoric Iberians - or with later Celtic invaders.

19 389i 389ii 390 391 392 393 385a 385b
14 13 - 24 11 13 15 11 14

Geographical Locale

%
Northern Spain [Basque] .60
Lombardy, Italy .55
Rostock, Mecklenburg .49
Freiburg, Baden-Wurttemburg .23